Recombinant Human DGUOK Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 32.1 kDa | AA Sequence : MAAGRLFLSRLRAPFSSMAKSPLEG VSSSRGLHAGRGPRRLSIEGNIAVG KSTFVKLLTKTYPEWHVATEPVATW QNIQAAGTQKACTAQSLGNLLDMMY REPARWSYTFQTFSFLSRLKVQLEP FPEKLLQARKPVQIFERSVYSDRYI FAKNLFENGSLSDIEWHIYQDWHSF LLWEFASRITLHGFIYLQASPQVCL KRLYQRAREEEKGIELAYLEQLHGQ HEAWLIHKTTKLHFEALMNIPVLVL DVNDDFSEEVTKQEDLMREVNTFVK NLTRTRPLEQKLISEEDLAANDILD YKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.