Name :
Recombinant Human DICER1 protein, MYC/DDK-tagged
Specification :
| Description : This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. | Source : HEK293 | Species : Human | Tag : MYC/DDK | Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. | Molecular Mass : 218.5 kDa | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 ug/mL as determined by microplate BCA method
Gene Information :
| Gene Name : DICER1 dicer 1, ribonuclease type III [ Homo sapiens ] | Official Symbol : DICER1 | Synonyms : DICER1; dicer 1, ribonuclease type III; Dicer1, Dcr 1 homolog (Drosophila); endoribonuclease Dicer; Dicer; dicer 1; double stranded RNA specific endoribonuclease; HERNA; K12H4.8 LIKE; KIAA0928; K12H4.8-LIKE; helicase MOI; helicase-moi; Dicer1, Dcr-1 homolog; helicase with RNAse motif; dicer 1, double-stranded RNA-specific endoribonuclease; DCR1; MNG1; | Gene ID : 23405 | mRNA Refseq : NM_030621 | Protein Refseq : NP_085124 | MIM : 606241 | UniProt ID : Q9UPY3 | Chromosome Location : 14q32.2 | Pathway : Gene expression, organism-specific biosystem; MicroRNA (miRNA) Biogenesis, organism-specific biosystem; Regulatory RNA pathways, organism-specific biosystem; Small Interfering RNA (siRNA) Biogenesis, organism-specific biosystem; mRNA processing, organism-specific biosystem; | Function : ATP binding; ATP-dependent helicase activity; double-stranded RNA binding; endonuclease activity; helicase activity; hydrolase activity; metal ion binding; miRNA binding; nucleotide binding; protein binding; ribonuclease III activity; ribonuclease III activity;
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