Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1, GST-tagged

Specification :
| Cat. No. : DNAJB1-4839H | Description : DNAJB1 is a member of heat shock proteins (HSPs) which are synthesized in cells in response to heat shock and other metabolic stresses and provide a transient state of thermotolerance. DNAJB1 is localized faintly throughout the cell in non-heat-shocked cells and accumulates in the nuclei and nucleoli in heat-shocked cells. The intracellular localization of DNAJB1 is very similar to that of HSP70. Overexpression of HSP40 reduces aggregate formation and suppresses apoptosis in a neuronal cell model of spinal and bulbar muscular atrophy (inherited neurodegenerative diseases caused by polyglutamine expansion). | Applications : Western Blot | Molecular Weight : 65 kDa | Expression System : E.coli | Species : Human | Form : Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. | Purity : > 90 % | Concentration : 0.2 ug/ul | Sequences : Full length | Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Pathways : Influenza A; Protein processing in endoplasmic reticulum