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Name :
Recombinant Human DPP4 Protein

Specification :
| Description : The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. | Source : HEK293 | Species : Human | Form : Lyophilized | Molecular Mass : 85.4 kDa | Protein Length : 766 | AA Sequence : MKTPWKVLLGLLGAAALVTIITVPV VLLNKGTDDATADSRKTYTLTDYLK NTYRLKLYSLRWISDHEYLYKQENN ILVFNAEYGNSSVFLENSTFDEFGH SINDYSISPDGQFILLEYNYVKQWR HSYTASYDIYDLNKRQLITEERIPN NTQWVTWSPVGHKLAYVWNNDIYVK IEPNLPSYRITWTGKEDIIYNGITD WVYEEEVFSAYSALWWSPNGTFLAY AQFNDTEVPLIEYSFYSDESLQYPK TVRVPYPKAGAVNPTVKFFVVNTDS LSSVTNATSIQITAPASMLIGDHYL CDVTWATQERISLQWLRRIQNYSVM DICDYDESSGRWNCLVARQHIEMST TGWVGRFRPSEPHFTLDGNSFYKII SNEEGYRHICYFQIDKKDCTFITKG TWEVIGIEALTSDYLYYISNEYKGM PGGRNLYKIQLSDYTKVTCLSCELN PERCQYYSVSFSKEAKYYQLRCSGP GLPLYTLHSSVNDKGLRVLEDNSAL DKMLQNVQMPSKKLDFIILNETKFW YQMILPPHFDKSKKYPLLLDVYAGP CSQKADTVFRLNWATYLASTENIIV ASFDGRGSGYQGDKIMHAINRRLGT FEVEDQIEAARQFSKMGFVDNKRIA IWGWSYGGYVTSMVLGSGSGVFKCG IAVAPVSRWEYYDSVYTERYMGLPT PEDNLDHYRNSTVMSRAENFKQVEY LLIHGTADDNVHFQQSAQISKALVD VGVDFQAMWYTDEDHGIASSTAHQH IYTHMSHFIKQCFSLP | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information :
| Gene Name : DPP4 dipeptidyl-peptidase 4 [ Homo sapiens (human) ] | Official Symbol : DPP4 | Synonyms : DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103; | Gene ID : 1803 | mRNA Refseq : NM_001935 | Protein Refseq : NP_001926 | MIM : 102720 | UniProt ID : P27487

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors