Recombinant Human EGFR protein

Specification :
| Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. | Source : CHO | Species : Human | Form : Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 | Molecular Mass : 97.5 kDa | AA Sequence : LEEKKVCQGTSNKLTQLGTFEDHFL SLQRMFNNCEVVLGNLEITYVQRNY DLSFLKTIQEVAGYVLIALNTVERI PLENLQIIRGNMYYENSYALAVLSN YDANKTGLKELPMRNLQEILHGAVR FSNNPALCNVESIQWRDIVSSDFLS NMSMDFQNHLGSCQKCDPSCPNGSC WGAGEENCQKLTKIICAQQCSGRCR GKSPSDCCHNQCAAGCTGPRESDCL VCRKFRDEATCKDTCPPLMLYNPTT YQMDVNPEGKYSFGATCVKKCPRNY VVTDHGSCVRACGADSYEMEEDGVR KCKKCEGPCRKVCNGIGIGEFKDSL SINATNIKHFKNCTSISGDLHILPV AFRGDSFTHTPPLDPQELDILKTVK EITGFLLIQAWPENRTDLHAFENLE IIRGRTKQHGQFSLAVVSLNITSLG LRSLKEISDGDVIISGNKNLCYANT INWKKLFGTSGQKTKIISNRGENSC KATGQVCHALCSPEGCWGPEPRDCV SCRNVSRGRECVDKCNLLEGEPREF VENSECIQCHPECLPQAMNITCTGR GPDNCIQCAHYIDGPHCVKTCPAGV MGENNTLVWKYADAGHVCHLCHPNC TYGCTGPGLEGCPTNGPKIPS | Purity : >95% as determined by SDS-PAGE and Coomassie blue staining | Concentration : Resuspend the protein in the desired concentration in proper buffer