Name :
Recombinant Human EGFR protein, His-Avi-tagged
Specification :
| Description : The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0. 22um filtered solution in PBS (pH 7. 4). | Molecular Mass : The protein has a predicted MW of 71. 5 kDa. Due to glycosylation, the protein migrates to 85- 110KDa based on Bis-Tris PAGE result. | Protein length : It contains Leu 25 – Ser645. | Endotoxin : Less than 0. 05EU per ug by the LAL method. | Purity : > 95% as determined by SDS-PAGE; > 95% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Information :
| Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens ] | Official Symbol : EGFR | Synonyms : ErbB; ErbB1; HER1; HER-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2. 7. 10; EC 2. 7. 10. 1; EGF R; EGFR; epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog); epidermal growth factor receptor; ERBB1PIG61;mENA; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | Gene ID : 1956 | mRNA Refseq : NM_005228 | Protein Refseq : NP_005219 | MIM : 131550 | UniProt ID : P00533
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