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Name :
Recombinant Human EGFR protein, His & S-tagged

Specification :
| Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. | Source : E. coli | Species : Human | Tag : His & S | Form : Freeze-dried powder | Molecular Mass : Predicted Molecular Mass: 37.5kDa | Protein length : Lys713~Asp984 (Accession # P00533) | Endotoxin : | Purity : >95% | Characteristic : The isoelectric point is 6.7. | Applications : SDS-PAGE; WB; ELISA; IP. | Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. | Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. | Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. | Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information :
| Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens (human) ] | Official Symbol : EGFR | Synonyms : ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor receptor | Gene ID : 1956 | mRNA Refseq : NM_001346897.1 | Protein Refseq : NP_001333826.1 | UniProt ID : P00533

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Author: Cholesterol Absorption Inhibitors