Name :
Active Recombinant Human ERBB2 Protein, Fc-tagged, Alexa Fluor 488 conjugated
Specification :
| Source : Mammalian cells | Species : Human | Tag : Fc | Form : Lyophilized | Bio-activity : Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer cell proliferation. The ED50 for this effect is typically 20-80 ng/mL in the presence of 0.6 μg/mL goat anti-hErbB2. | Molecular Mass : Recombinant Human ERBB2, Fc Chimera has a calculated MW of 96.8 kDa (monomer). In SDS-PAGE migrates as 125-130 kDa, reducing conditions220-250 kDa, non-reducing conditions. | N-terminal Sequence Analysis : Thr 23 | Purity : > 90 % by SDS-PAGE and analyzed by silver stain | Characteristic : Disulfide-linked homodimerLabeled with Alexa Fluor 488 via aminesExcitation Wavelength: 488 nmEmission Wavelength: 515-545 nm | Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade). | Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS.
Gene Information :
| Gene Name : ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Homo sapiens ] | Official Symbol : ERBB2 | Synonyms : ERBB2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian); NGL, v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); receptor tyrosine-protein kinase erbB-2; CD340; HER 2; HER2; NEU; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); NGL; TKR1; HER-2; MLN 19; HER-2/neu; | Gene ID : 2064 | mRNA Refseq : NM_001005862 | Protein Refseq : NP_001005862 | MIM : 164870 | UniProt ID : P04626
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