Recombinant Human ENG Protein, Trx-6His-tagged

Specification :
| Description : This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | Source : E. coli | Species : Human | Tag : Trx-6His | Form : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.4 | Molecular Mass : 33.6kD | AA Sequence : MSDKIIHLTDDSFDTDVLKADGAIL VDFWAEWCGPCKMIAPILDEIADEY QGKLTVAKLNIDQNPGTAPKYGIRG IPTLLLFKNGEVAATKVGALSKGQL KEFLDANLAGSGSGHMHHHHHHSSG LVPRGSGMKETAAAKFERQHMDSPD LGTDDDDKAMETVHCDLQPVGPERD EVTYTTSQVSKGCVAQAPNAILEVH VLFLEFPTGPSQLELTLQASKQNGT WPREVLLVLSVNSSVFLHLQALGIP LHLAY | Endotoxin : Endotoxin level is | Purity : >95% as determined by SDS-PAGE and Coomassie blue staining | Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.