Name :
Recombinant Human EPCAM Protein
Specification :
| Description : This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] | Source : Wheat Germ | Species : Human | Form : Liquid | Molecular Mass : 34.9 kDa | AA Sequence : MAPPQVLAFGLLLAAATATFAAAQE ECVCENYKLAVNCFVNNNRQCQCTS VGAQNTVICSKLAAKCLVMKAEMNG SKLGRRAKPEGALQNNDGLYDPDCD ESGLFKAKQCNGTSTCWCVNTAGVR RTDKDTEITCSERVRTYWIIIELKH KAREKPYDSKSLRTALQKEITTRYQ LDPKFITSILYENNVITIDLVQNSS QKTQNDVDIADVAYYFEKDVKGESL FHSKKMDLTVNGEQLDLDPGQTLIY YVDEKAPEFSMQGLKAGVIAVIVVV VIAVVAGIVVLVISRKKRMAKYEKA EIKEMGEMHRELNA | Applications : Antibody ProductionFunctional StudyCompound Screening | Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis. | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 25 mM Tris-HCl of pH 8.0 containing 2% glycerol.
Gene Information :
| Gene Name : EPCAM epithelial cell adhesion molecule [ Homo sapiens ] | Official Symbol : EPCAM | Synonyms : EPCAM; epithelial cell adhesion molecule; antigen identified by monoclonal AUA1 , M4S1, MIC18, TACSTD1, tumor associated calcium signal transducer 1; 17 1A; 323/A3; CD326; CO 17A; EGP 2; EGP34; EGP40; Ep CAM; ESA; GA733 2; HEA125; KS1/4; KSA; Ly74; MH99; MK 1; MOC31; TACST 1; TROP1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); M4S1; MK-1; DIAR5; EGP-2; MIC18; EGP314; HNPCC8; TACSTD1; GA733-2; | Gene ID : 4072 | mRNA Refseq : NM_002354 | Protein Refseq : NP_002345 | MIM : 185535 | UniProt ID : P16422
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