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Name :
Recombinant Human EphA3 Protein, GST-tagged

Specification :
| Description : This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 136.5 kDa | AA Sequence : MDCQLSILLLLSCSVLDSFGELIPQ PSNEVNLLDSKTIQGELGWISYPSH GWEEISGVDEHYTPIRTYQVCNVMD HSQNNWLRTNWVPRNSAQKIYVELK FTLRDCNSIPLVLGTCKETFNLYYM ESDDDHGVKFREHQFTKIDTIAADE SFTQMDLGDRILKLNTEIREVGPVN KKGFYLAFQDVGACVALVSVRVYFK KCPFTVKNLAMFPDTVPMDSQSLVE VRGSCVNNSKEEDPPRMYCSTEGEW LVPIGKCSCNAGYEERGFMCQACRP GFYKALDGNMKCAKCPPHSSTQEDG SMNCRCENNYFRADKDPPSMACTRP PSSPRNVISNINETSVILDWSWPLD TGGRKDVTFNIICKKCGWNIKQCEP CSPNVRFLPRQFGLTNTTVTVTDLL AHTNYTFEIDAVNGVSELSSPPRQF AAVSITTNQAAPSPVLTIKKDRTSR NSISLSWQEPEHPNGIILDYEVKYY EKQEQETSYTILRARGTNVTISSLK PDTIYVFQIRARTAAGYGTNSRKFE FETSPDSFSISGESSQVVMIAISAA VAIILLTVVIYVLIGRFCGYKSKHG ADEKRLHFGNGHLKLPGLRTYVDPH TYEDPTQAVHEFAKELDATNISIDK VVGAGEFGEVCSGRLKLPSKKEISV AIKTLKVGYTEKQRRDFLGEASIMG QFDHPNIIRLEGVVTKSKPVMIVTE YMENGSLDSFLRKHDAQFTVIQLVG MLRGIASGMKYLSDMGYVHRDLAAR NILINSNLVCKVSDFGLSRVLEDDP EAAYTTRGGKIPIRWTSPEAIAYRK FTSASDVWSYGIVLWEVMSYGERPY WEMSNQDVIKAVDEGYRLPPPMDCP AALYQLMLDCWQKDRNNRPKFEQIV SILDKLIRNPGSLKIITSAAARPSN LLLDQSNVDITTFRTTGDWLNGVWT AHCKEIFTGVEYSSCDTIAKISTDD MKKVGVTVVGPQKKIISSIKALETQ SKNGPVPV | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : EphA3 EPH receptor A3 [ Homo sapiens ] | Official Symbol : EphA3 | Synonyms : EphA3; EPH receptor A3; EphA3 , ETK, ETK1, TYRO4; ephrin type-A receptor 3; HEK; HEK4; EPH-like kinase 4; human embryo kinase 1; eph-like tyrosine kinase 1; TYRO4 protein tyrosine kinase; tyrosine-protein kinase receptor ETK1; EK4; ETK; ETK1; TYRO4; | Gene ID : 2042 | mRNA Refseq : NM_005233 | Protein Refseq : NP_005224 | MIM : 179611 | UniProt ID : P29320

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Author: Cholesterol Absorption Inhibitors