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Name :
Active Recombinant Human EPHB1 Protein, His-tagged

Specification :
| Description : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. | Source : HEK293 | Species : Human | Tag : His | Form : Liquid | Bio-activity : Measured by its binding ability in a functional ELISA with Human EFNB1. | Molecular Mass : 59.2 kDa (529aa) | AA Sequence : MEETLMDTRTATAELGWTANPASGW EEVSGYDENLNTIRTYQVCNVFEPN QNNWLLTTFINRRGAHRIYTEMRFT VRDCSSLPNVPGSCKETFNLYYYET DSVIATKKSAFWSEAPYLKVDTIAA DESFSQVDFGGRLMKVNTEVRSFGP LTRNGFYLAFQDYGACMSLLSVRVF FKKCPSIVQNFAVFPETMTGAESTS LVIARGTCIPNAEEVDVPIKLYCNG DGEWMVPIGRCTCKPGYEPENSVAC KACPAGTFKASQEAEGCSHCPSNSR SPAEASPICTCRTGYYRADFDPPEV ACTSVPSGPRNVISIVNETSIILEW HPPRETGGRDDVTYNIICKKCRADR RSCSRCDDNVEFVPRQLGLTECRVS ISSLWAHTPYTFDIQAINGVSSKSP FPPQHVSVNITTNQAAPSTVPIMHQ VSATMRSITLSWPQPEQPNGIILDY EIRYYEKEHNEFNSSMARSQTNTAR IDGLRPGMVYVVQVRARTVAGYGKF SGKMCFQTLTDDDYKSELREQLP | Endotoxin : | Purity : > 95% by SDS-PAGE | Applications : SDS-PAGE, Bioactivity | Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.25 mg/mL (determined by absorbance at 280nm) | Storage Buffer : In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information :
| Gene Name : EPHB1 EPH receptor B1 [ Homo sapiens (human) ] | Official Symbol : EPHB1 | Synonyms : EPHB1; EPH receptor B1; ELK; NET; Hek6; EPHT2; ephrin type-B receptor 1; EK6; EPH-like kinase 6; eph tyrosine kinase 2; neuronally-expressed EPH-related tyrosine kinase; soluble EPHB1 variant 1; tyrosine-protein kinase receptor EPH-2; EC 2.7.10.1 | Gene ID : 2047 | mRNA Refseq : NM_004441 | Protein Refseq : NP_004432 | MIM : 600600 | UniProt ID : P54762

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Author: Cholesterol Absorption Inhibitors