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Name :
Recombinant Human EphB3 Protein, GST-tagged

Specification :
| Description : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 136.7 kDa | AA Sequence : MARARPPPPPSPPPGLLPLLPPLLL LPLLLLPAGCRALEETLMDTKWVTS ELAWTSHPESGWEEVSGYDEAMNPI RTYQVCNVRESSQNNWLRTGFIWRR DVQRVYVELKFTVRDCNSIPNIPGS CKETFNLFYYEADSDVASASSPFWM ENPYVKVDTIAPDESFSRLDAGRVN TKVRSFGPLSKAGFYLAFQDQGACM SLISVRAFYKKCASTTAGFALFPET LTGAEPTSLVIAPGTCIPNAVEVSV PLKLYCNGDGEWMVPVGACTCATGH EPAAKESQCRPCPPGSYKAKQGEGP CLPCPPNSRTTSPAASICTCHNNFY RADSDSADSACTTVPSPPRGVISNV NETSLILEWSEPRDLGGRDDLLYNV ICKKCHGAGGASACSRCDDNVEFVP RQLGLTERRVHISHLLAHTRYTFEV QAVNGVSGKSPLPPRYAAVNITTNQ AAPSEVPTLRLHSSSGSSLTLSWAP PERPNGVILDYEMKYFEKSEGIAST VTSQMNSVQLDGLRPDARYVVQVRA RTVAGYGQYSRPAEFETTSERGSGA QQLQEQLPLIVGSATAGLVFVVAVV VIAIVCLRKQRHGSDSEYTEKLQQY IAPGMKVYIDPFTYEDPNEAVREFA KEIDVSCVKIEEVIGAGEFGEVCRG RLKQPGRREVFVAIKTLKVGYTERQ RRDFLSEASIMGQFDHPNIIRLEGV VTKSRPVMILTEFMENCALDSFLRL NDGQFTVIQLVGMLRGIAAGMKYLS EMNYVHRDLAARNILVNSNLVCKVS DFGLSRFLEDDPSDPTYTSSLGGKI PIRWTAPEAIAYRKFTSASDVWSYG IVMWEVMSYGERPYWDMSNQDVINA VEQDYRLPPPMDCPTALHQLMLDCW VRDRNLRPKFSQIVNTLDKLIRNAA SLKVIASAQSGMSQPLLDRTVPDYT TFTTVGDWLDAIKMGRYKESFVSAG FASFDLVAQMTAEDLLRIGVTLAGH QKKILSSIQDMRLQMNQTLPVQV | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : EphB3 EPH receptor B3 [ Homo sapiens ] | Official Symbol : EphB3 | Synonyms : EphB3; EPH receptor B3; EphB3 , ETK2; ephrin type-B receptor 3; Hek2; Tyro6; EK2; EPH-like kinase 2; embryonic kinase 2; human embryo kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; tyrosine-protein kinase TYRO6; ETK2; HEK2; TYRO6; | Gene ID : 2049 | mRNA Refseq : NM_004443 | Protein Refseq : NP_004434 | MIM : 601839 | UniProt ID : P54753

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Author: Cholesterol Absorption Inhibitors