Recombinant Human EPHB4 Protein, GST-tagged

Specification :
| Description : Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 134.7 kDa | AA Sequence : MELRVLLCWASLAAALEETLLNTKL ETADLKWVTFPQVDGQWEELSGLDE EQHSVRTYEVCDVQRAPGQAHWLRT GWVPRRGAVHVYATLRFTMLECLSL PRAGRSCKETFTVFYYESDADTATA LTPAWMENPYIKVDTVAAEHLTRKR PGAEATGKVNVRTLRLGPLSKAGFY LAFQDQGACMALLSLHLFYKKCAQL TVNLTRFPETVPRELVVPVAGSCVV DAVPAPGPSPSLYCREDGQWAEQPV TGCSCAPGFEAAEGNTKCRACAQGT FKPLSGEGSCQPCPANSHSNTIGSA VCQCRVGYFRARTDPRGAPCTTPPS APRSVVSRLNGSSLHLEWSAPLESG GREDLTYALRCRECRPGGSCAPCGG DLTFDPGPRDLVEPWVVVRGLRPDF TYTFEVTALNGVSSLATGPVPFEPV NVTTDREVPPAVSDIRVTRSSPSSL SLAWAVPRAPSGAVLDYEVKYHEKG AEGPSSVRFLKTSENRAELRGLKRG ASYLVQVRARSEAGYGPFGQEHHSQ TQLDESEGWREQLALIAGTAVVGVV LVLVVIVVAVLCLRKQSNGREAEYS DKHGQYLIGHGTKVYIDPFTYEDPN EAVREFAKEIDVSYVKIEEVIGAGE FGEVCRGRLKAPGKKESCVAIKTLK GGYTERQRREFLSEASIMGQFEHPN IIRLEGVVTNSMPVMILTEFMENGA LDSFLRLNDGQFTVIQLVGMLRGIA SGMRYLAEMSYVHRDLAARNILVNS NLVCKVSDFGLSRFLEENSSDPTYT SSLGGKIPIRWTAPEAIAFRKFTSA SDAWSYGIVMWEVMSFGERPYWDMS NQDVINAIEQDYRLPPPPDCPTSLH QLMLDCWQKDRNARPRFPQVVSALD KMIRNPASLKIVARENGGASHPLLD QRQPHYSAFGSVGEWLRAIKMGRYE ESFAAAGFGSFELVSQISAEDLLRI GVTLAGHQKKILASVQHMKSQAKPG TPGGTGGPAPQY | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.