Recombinant Human EPHB4 Protein, His-tagged

Specification :
| Description : EphB4, also known ephrin type-B receptor 4, is a member of the Eph receptor tyrosine kinase family. It binds transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. This protein plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. And the signaling of this protein controls cellular repulsion and segregation form EFNB2-expressing cells. And it also plays a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. | Source : Insect cell | Species : Human | Tag : His | Form : Liquid | Molecular Mass : 58.1 kDa (532aa) | AA Sequence : LEETLLNTKLETADLKWVTFPQVDG QWEELSGLDEEQHSVRTYEVCDVQR APGQAHWLRTGWVPRRGAVHVYATL RFTMLECLSLPRAGRSCKETFTVFY YESDADTATALTPAWMENPYIKVDT VAAEHLTRKRPGAEATGKVNVKTLR LGPLSKAGFYLAFQDQGACMALLSL HLFYKKCAQLTVNLTRFPETVPREL VVPVAGSCVVDAVPAPGPSPSLYCR EDGQWAEQPVTGCSCAPGFEAAEGN TKCRACAQGTFKPLSGEGSCQPCPA NSHSNTIGSAVCQCRVGYFRARTDP RGAPCTTPPSAPRSVVSRLNGSSLH LEWSAPLESGGREDLTYALRCRECR PGGSCAPCGGDLTFDPGPRDLVEPW VVVRGLRPDFTYTFEVTALNGVSSL ATGPVPFEPVNVTTDREVPPAVSDI RVTRSSPSSLSLAWAVPRAPSGAVL DYEVKYHEKGAEGPSSVRFLKTSEN RAELRGLKRGASYLVQVRARSEAGY GPFGQEHHSQTQLDESEGWREQLAV EHHHHHH | N-terminal Sequence Analysis : Leu 16 | Endotoxin : | Purity : > 90% by SDS-PAGE | Notes : For research use only. This product is not intended or approved for human, diagnostics or veterin. | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade.Avoid repeated freezing and thawing cycles. | Concentration : 0.25 mg/mL (determined by Absorbance at 280nm) | Storage Buffer : In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.