Recombinant Human EPHB4 Protein (Met1-Ala539), His-tagged, Biotinylated

Specification :
| Description : Ephrin type-B receptor 4 is a protein that in humans is encoded by the EphB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. | Source : Baculovirus-Insect Cells | Species : Human | Tag : His | Predicted N Terminal : Leu 16 | Form : Lyophilized from sterile Sterile PBS. Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. | Molecular Mass : The recombinant EphB4 consists of 535 amino acids and predicts a molecular mass of 58.5 kDa. | Protein length : Met1-Ala539 | Endotoxin : | Purity : > 95 % as determined by SDS-PAGE. | Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade. | Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4℃ before opening to recover the entire contents. | Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.