Name :
Active Recombinant Human ERBB2 protein
Specification :
| Source : HEK293 | Species : Human | Tag : N/A | Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. | Bio-activity : Immobilized Human Her2, Tag Free at 1 μg/mL (100 μL/well)can bind Trastuzumab with a linear range of 0.2-2 ng/mL.Immobilized Human Her2, Tag Free at 1 μg/mL (100 μL/well) can bind Bispecific Antibody (Her2 × Her3) with a linear range of 0.1-2 ng/mL.Immobilized Human Her2, Tag Free at 1 μg/mL (100 μL/well) can bind Pertuzumab Biosimilar with a linear range of 0.1-4 ng/mL. | Molecular Mass : This protein carries no “tag”The protein has a calculated MW of 70.1 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. | Protein Length : Thr23-Thr652 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please protect from light and avoid repeated freeze-thaw cycles.This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Information :
| Gene Name : ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [ Homo sapiens ] | Official Symbol : ERBB2 | Synonyms : ERBB2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian); NGL, v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); receptor tyrosine-protein kinase erbB-2; CD340; HER 2; HER2; NEU; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog); NGL; TKR1; HER-2; MLN 19; HER-2/neu; | Gene ID : 2064 | mRNA Refseq : NM_001005862 | Protein Refseq : NP_001005862 | MIM : 164870 | UniProt ID : P04626
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