Recombinant Human F11R Protein

Specification :
| Description : Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5′ alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. | Source : HEK293 | Species : Human | Form : Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 50mM NaCl, 100mM Glycine, pH 7.5. | Molecular Mass : 23.9 kDa | Protein length : Ser28-Val238 | Endotoxin : | Purity : >95% as determined by SDS-PAGE and Coomassie blue staining | Storage : Stable for at least 6 months from date of receipt under proper storage and handling conditions. | Concentration : Resuspend the protein to the desired concentration in proper buffer.