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Name :
Active Recombinant Human FAS protein, hFc&His-tagged

Specification :
| Source : HEK293 | Species : Human | Tag : hFc&His | Form : Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. | Bio-activity : 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant Human Fas Ligand at 2 μg/mL (100 μL/well) can bind recombinant Human FAS. The EC50 of Human FAS is 6.23 ng/mL.2.Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat Human acute T cell leukemia cells. The ED50 for this effect is typically 16.5-66 ng/mL in the presence of 5 ng/mL Recombinant Human Fas Ligand. | Molecular Mass : 50-70 kDa | Protein Length : Gln26-Asn173 | Endotoxin : | Purity : > 90% by SDS-PAGE. | Storage : Store the lyophilized protein at -20°C to -80 °C for long term.After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. | Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Gene Information :
| Gene Name : FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ] | Official Symbol : FAS | Synonyms : FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; | Gene ID : 355 | mRNA Refseq : NM_000043 | Protein Refseq : NP_000034 | MIM : 134637 | UniProt ID : P25445

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors