Active Recombinant Human Fas (TNF receptor superfamily, member 6)

Specification :
| Cat. No. : CSF3R-3815H | Description : CSF3R which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3, a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. | Source : Human | Host : Human Cells | Form : Lyophilized from sterile PBS, pH 7.4, Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. | Purity : > 95 % as determined by SDS-PAGE | Bio-activity : Measured by its ability to inhibit the GCSF-induced proliferation of NFS-60 mouse myeloid cells. The ED50 for this effect is typically 1-4 ng/ml in the presence of 0.125 ng/mL of recombinant human GCSF. | Endotoxin : | Stability : Samples are stable for up to twelve months from date of receipt at -70°C. | Predicted N terminal : Glu 25 | Molecular Mass : The mature recombinant human CSF3R is a disulfide-linked homodimeric protein. The reduced monomer consists of 835 amino acids and predicts a molecular mass of 93.3 KDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rh CSF3R monomer is approximately 120-130 KDa due to glycosylation. | Storage : Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.