Name :
Active Recombinant Human FASLG, Fc-tagged
Specification :
| Description : Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development. | Source : HEK293 Cells | Species : Human | Tag : Fc | Form : Lyophilized. Contains PBS. | Bio-activity : Induces apoptosis of human Jurkat T cells at a concentration of | Molecular Mass : ~50kDa (SDS-PAGE) | Purity : ≥95% (SDS-PAGE) | Stability : Stable for at least 6 months after receipt when stored at -20°C. | Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. | Concentration : 0.1mg/ml after reconstitution.
Gene Information :
| Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ] | Official Symbol : FASLG | Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1; | Gene ID : 356 | mRNA Refseq : NM_000639 | Protein Refseq : NP_000630 | MIM : 134638 | UniProt ID : P48023 | Chromosome Location : 1q23 | Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; | Function : cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding;
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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