Recombinant Human F3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 33.1 kDa | AA Sequence : METPAWPRVPRPETAVARTLLLGWV FAQVAGASGTTNTVAAYNLTWKSTN FKTILEWEPKPVNQVYTVQISTKSG DWKSKCFYTTDTECDLTDEIVKDVK QTYLARVFSYPAGNVESTGSAGEPL YENSPEFTPYLETNLGQPTIQSFEQ VGTKVNVTVEDERTLVRRNNTFLSL RDVFGKDLIYTLYYWKSSSSGKKTA KTNTNEFLIDVDKGENYCFSVQAVI PSRTVNRKSTDSPVECMGQEKGEFR EIFYIIGAVVFVVIILVIILAISLH KCRKAGVGQSWKENSPLNVSTRTRP LEQKLISEEDLAANDILDYKDDDDK V | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.