Active Recombinant Human FASLG Protein (Gln130-Leu281), N-His-SUMO tagged, Animal-free, Carrier-free

Specification :
| Description : Fas Ligand (FasL) is a 17.34 kDa tumor necrosis factor with 152 amino acid residues. FasL is expressed from lymphoid tissue and secreted to blood. Binding to its receptor, TNFRSF6/FAS, leads to induce apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. | Source : E. coli | Species : Human | Tag : N-His-SUMO | Form : Lyophilized | Bio-activity : Measure by its ability to induce apoptosis in Jurkat cells. The ED50 for this effect is 1 × 10⁶ IU/mg. | Molecular Mass : The protein has a calculated MW of 29.51 kDa.The protein migrates as 30-35 kDa under reducing condition (SDS-PAGE analysis). | Protein Length : Gln130-Leu281 | Endotoxin : | Purity : >98% as determined by SDS-PAGE analysis. | Storage : This product is stable after storage at:-20 centigrade for 12 months in lyophilized state from date of receipt.-20 or -80 centigrade for 1 month under sterile conditions after reconstitution.Avoid repeated freeze/thaw cycles. | Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0. | Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. | Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.