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Name :
Recombinant Human Fas Ligand Inhibitor, Fc-tagged

Specification :
| Species : Human | Tag : Fc | Form : 50 μg lyophilized, contains PBS. | Molecular Mass : ~56 kDa | Endotoxin : Endotoxin content is | Purity : ≥95% as determined by SDS-PAGE. | Characteristic : Inhibits the apoptosis-inducing activity of Fas Ligand. Binds FasL. | Applications : Functional Application: Inhibition of FAS Ligand activity in human and mouse: The apoptosis-inducing activity of FasL is inhibited by concentrations of 20-100 μg/mL of the fusion protein. | Usage : For in vitro research use only. Not for use in diagnostics or in humans. | Storage : Store at -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles (activity may decrease). | Warning : No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.

Gene Information :
| Gene Name : FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ] | Official Symbol : FAS | Synonyms : FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; | Gene ID : 355 | mRNA Refseq : NM_000043 | Protein Refseq : NP_000034 | MIM : 134637 | UniProt ID : P25445 | Chromosome Location : 10q24.1 | Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Alzheimers disease, organism-specific biosystem; | Function : binding; identical protein binding; kinase binding; protein binding; receptor activity; receptor activity; signal transducer activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;

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Author: Cholesterol Absorption Inhibitors