Share this post on:

Name :
Recombinant Human Fas Ligand (TNF superfamily, member 6), His-tagged

Specification :
| Cat. No. : FASLG-5412H | Description : FASLG is a type-IItransmembrane protein that belongs to the tumor necrosis factor (TNF) family.Its binding with its receptor induces apoptosis. Fas ligand/receptorinteractions play an important role in the regulation of the immune systemand the progression of cancer. | Source : CHO cells | Species : Human | Form : Lyophilized withoutadditives. | Molecular Weight : 17.9 kDa | Purity : | Endotoxin Level : | Biological Activity : Determined by itsability to induce cytotoxicity in Jurkat cells in the absence of anycross-linking. The EDSO for this effect is | Specific Activity : | Reconstitution : Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. | Storage : Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles. | OfficialSymbol : FASLG

Gene Information :
| Gene Name : FASLG Fas ligand (TNFsuperfamily, member 6) [ Homo sapiens ] | Synonyms : FASLG; Fas ligand(TNF superfamily, member 6); FASL; CD178; CD95L; CD95-L; TNFSF6; APT1LG1; tumor necrosis factor ligand superfamily member 6; APTL; CD95ligand; OTTHUMP00000032708; fas antigen ligand; apoptosis antigen ligand;apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand)superfamily, member 6 | Gene ID : 356 | mRNA Refseq : NM_000639 | Protein Refseq : NP_000630 | MIM : 134638 | UniProt ID : P48023 | Chromosome Location : 1q23 | Pathway : Activationof Pro-Caspase 8; Africantrypanosomiasis; Allograft rejection;Apoptosis; Autoimmune thyroid disease; Calcineurin-regulatedNFAT-dependent transcription in lymphocytes; Calcium signaling in the CD4+ TCR pathway; Caspase-8 is formed from proCaspase-8; Death Receptor Signalling; FoxO family signaling; Influenza A; MAPKsignaling pathway; Measles; Pathways in cancer; Type I diabetes mellitus | Function : cytokine activity;protein binding; receptor binding; tumor necrosis factor receptor binding

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
TGF-alpha Proteinweb
E/Envelope ProteinSpecies
Popular categories:
CD218b/IL-18RAP
Langerin/CD207

Share this post on:

Author: Cholesterol Absorption Inhibitors