Recombinant Human Fas (TNF receptor superfamily, member 6)

Specification :
| Cat. No. : FAS-5411H | Description : The FAS is a deathreceptor on the surface of cells that leads to programmed cell death(apoptosis). It is one of two apoptosis pathways, the other being themitochondrial pathway. FasR is located on chromosome 10 in humans and 19 inmice. Similar sequences related by evolution are found in most mammals. | Source : E. coli | Species : Human | Form : Lyophilized withoutadditives. | Molecular Weight : 17.6 kDa | Endotoxin Level : | Purity : >95% asdetermined by SDS-PAGE and HPLC analyses. | Biological Activity : Determined by itsability to inhibit the cytotoxicity of Jurkat cells. The EDSO is between10-15 pg/ml in the presence of 2 ng/ml of human Fast. | Reconstitution : Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. | Storage : Lyophilized proteinis stable for 2 years at -20°C. Reconstituted protein is stable for 1 week at2-4°C or for 3 months in working aliquots with a carrier protein (0.1%HSA orBSA) at -20°C. Please note that the addition of any carrier protein into thisproduct may produce unwanted endotoxin. This depends upon the particularapplication employed. Avoid repeated freeze-thaw cycles. | OfficialSymbol : FAS