Recombinant Human Fas (TNF receptor superfamily, member 6)

Specification :
| Cat. No. : FAS-3814H | Description : FAS is a member of the tumor necrosis factor (TNF)/nerve growth factor (NGF) receptor superfamily. FAS is highly expressed on the surface of a number of cell types including epithelial cells, hepatocytes, activated mature lymphocytes and other tumor cells. This receptor contains a death domain and has been shown to play a central role in the physiological regulation of programmed cell death (PCD, apoptosis) upon ligation of Fas ligand (Fas-L). | Source : Human | Host : Human Cells | Form : Lyophilized from sterile PBS, pH 7.4, Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. | Purity : > 95 % as determined by SDS-PAGE | Endotoxin : | Stability : Samples are stable for up to twelve months from date of receipt at -70°C. | Predicted N terminal : Gln 26 | Molecular Mass : The recombinant human FAS chimera is a disulfide-linked homodimeric protein generated after removal of the signal peptide. The reduced monomer consists of 386 amino acids and has a predicted molecular mass of 43.4 kDa. In SDS-PAGE under reducing conditions, the monomer migrates as an approximately 55-60 kDa protein due to glycosylation. | Storage : Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.