Active Recombinant Human Fc Receptor-Like 5, His-tagged

Specification :
| Cat. No. : FCRL5-506H | Description : FCRL5 isa 120 kDa protein with sequence homology to classical Fc receptors. They are differentiallyexpressed within the B cell lineage and can either promote or inhibit B cellproliferation and activation. According to R&D Systems testing, FCRL5binds to purified human IgG with high affinity. Mature human FCRL5 consistsof a 836 amino acid (aa) extracellular domain (ECD) with nine Ig-like domains,a 21 aa transmembrane segment, and a 105 aa cytoplasmic domain with one immunotyrosineactivation motif (ITAM) and two immunotyrosine inhibitory motifs (ITIMs). | Source : Mammalian cells | Form : Lyophilized from a0.2 um filtered solution in PBS. | N-terminalSequence : Gln16 predicted | MolecularWeight : 91.5 kDa | Activity : Measuredby its ability to bind human IgG with an estimated KD | Endotoxin Level : | SDS-PAGE : 110-120kDa, reducing conditions. | Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. | Reconstitution : Reconstitute at 100μg/mLin PBS. | Storage : Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution.