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Name :
Recombinant Human FBXO6 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 33.9 kDa | AA Sequence : MDAPHSKAALDSINELPENILLELF THVPARQLLLNCRLVCSLWRDLIDL MTLWKRKCLREGFITKDWDQPVADW KIFYFLRSLHRNLLRNPCAEEDMFA WQIDFNGGDRWKVESLPGAHGTDFP DPKVKKYFVTSYEMCLKSQLVDLVA EGYWEELLDTFRPDIVVKDWFAARA DCGCTYQLKVQLASADYFVLASFEP PPVTIQQWNNATWTEVSYTFSDYPR GVRYILFQHGGRDTQYWAGWYGPRV TNSSIVVSPKMTRNQASSEAQPGQK HGQEEAAQSPYRAVVQIFTRTRPLE QKLISEEDLAANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : FBXO6 F-box protein 6 [ Homo sapiens (human) ] | Official Symbol : FBXO6 | Synonyms : FBXO6; F-box protein 6; F box only protein 6; F-box only protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2; | Gene ID : 26270 | mRNA Refseq : NM_018438 | Protein Refseq : NP_060908 | MIM : 605647 | UniProt ID : Q9NRD1

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors