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Name :
Recombinant Human Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64), AVI-tagged

Specification :
| Cat. No. : FCGR1A-3818H | Description : High affinity immunoglobulin gamma Fc receptor IA , also known as IgG Fc receptor IA (FCGR1A) and CD64, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity. CD64 belongs to the immunoglobulin superfamily. It is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. | Source : Human | Host : Human Cells | Form : Lyophilized from sterile PBS , pH 7.4. Normally 5 % – 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. | Purity : > 95 % as determined by SDS-PAGE | Endotoxin : | Stability : Samples are stable for up to twelve months from date of receipt at -70°C. | Predicted N terminal : Gln 16 | Molecular Mass : The secreted recombinant human CD64 consists of 307 amino acids and has a predicted molecular mass of 34.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD64 is approximately 50-55 kDa due to glycosylation. | Storage : Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information :
| Gene Name : FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) [ Homo sapiens ] | Official Symbol : FCGR1A | Synonyms : FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); CD64; FCRI; CD64A; IGFR1; FLJ18345; FCGR1A; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64); FcRI; CD64 antigen | Gene ID : 2209 | mRNA Refseq : NM_000566 | Protein Refseq : NP_000557 | MIM : 146760 | UniProt ID : P12314 | Chromosome Location : 1q21.2-q21.3 | Pathway : Fc gamma R-mediated phagocytosis; Hematopoietic cell lineage; Leishmania infection; Systemic lupus erythematosus | Function : receptor signaling protein activity; IgG binding; protein binding; receptor activity

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Author: Cholesterol Absorption Inhibitors