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Name :
Active Recombinant Human FCGR2A protein(167 Arg), His-tagged

Specification :
| Source : HEK293 | Species : Human | Tag : His | Form : Lyophilized from sterile PBS, pH 7.5Normally 5 % trehalose, 5 % mannitol and 0.01% Tween80 are added as protectants before lyophilization. | Bio-activity : 1. Measured by its ability to bind biotinylated human IgG2 in functional ELISA.2. Loaded Anti-CD32A Antibody, Mouse Monoclonal on AMC Biosensor, can bind CD32A Protein, Human, Recombinant (167 Arg, His Tag) with an affinity constant of 6.8 nM as determined by Octet RED System. | Molecular Mass : The recombinant human FCGR2A consists of 196 amino acids after removal of the signal peptide and predicts a molecular mass of 22 kDa. It migrates as an approximately 30 kDa protein due to glycosylation by SDS-PAGE under reducing conditions. | Protein length : Met1-Ile218 | Endotoxin : | Purity : > 97 % as determined by SDS-PAGE | Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°CStore it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information :
| Gene Name : FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [ Homo sapiens ] | Official Symbol : FCGR2A | Synonyms : FCGR2A; CD32; CD32A; CDw32; IGFR2; fcRII-a; fc-gamma-RIIa; FCG2; FcGR; FCGR2; FCGR2A1; MGC23887; MGC30032; | Gene ID : 2212 | mRNA Refseq : NM_001136219.1 | Protein Refseq : NP_001129691.1 | MIM : 146790 | UniProt ID : P12318

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors