Active Recombinant Human FCGR2B, His-tagged

Specification :
| Description : The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. | Source : Human Cells | Species : Human | Tag : His | Predicted N Terminal : Ala 46 | Form : Lyophilized from sterile PBS , pH 7.4. Normally 5 % – 8 % trehalose and mannitol are added as protectants before lyophilization. | Bio-activity : Immobilized human CD32b-AVI-His at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.20-0.48 μg/ml. | Molecular Mass : The recombinant mature human CD32b consists of 214 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 30-35 kDa protein due to glycosylation | Endotoxin : | Purity : > 95 % as determined by SDS-PAGE | Stability : Samples are stable for up to twelve months from date of receipt at -70℃ | Storage : Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products.