Recombinant Human FGFR4 Protein (22-369aa), C-His tagged

Specification :
| Description : The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. | Source : Baculovirus | Species : Human | Tag : C-His | Form : Liquid | Molecular Mass : 39.5 kDa (356aa) | Protein Length : 22-369aa | AA Sequence : LEASEEVELEPCLAPSLEQQEQELT VALGQPVRLCCGRAERGGHWYKEGS RLAPAGRVRGWRGRLEIASFLPEDA GRYLCLARGSMIVLQNLTLITGDSL TSSNDDEDPKSHRDPSNRHSYPQQA PYWTHPQRMEKKLHAVPAGNTVKFR CPAAGNPTPTIRWLKDGQAFHGENR IGGIRLRHQHWSLVMESVVPSDRGT YTCLVENAVGSIRYNYLLDVLERSP HRPILQAGLPANTTAVVGSDVELLC KVYSDAQPHIQWLKHIVINGSSFGA DGFPYVQVLKTADINSSEVEVLYLR NVSAEDAGEYTCLAGNSIGLSYQSA WLTVLPEEDPTWTAAAPEARYTDLE HHHHHH | Endotoxin : | Purity : > 90% by SDS-PAGE | Applications : SDS-PAGE | Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.25 mg/mL (determined by absorbance at 280nm) | Storage Buffer : Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol