Active Recombinant Human FGR Protein, GST/His-tagged

Specification :
| Description : This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq | Source : Insect Cell | Species : Human | Tag : GST/His | Form : Liquid | Bio-activity : 16 pmol/μg x min | Molecular Mass : 93.934 kDa | Applications : Functional StudySDS-PAGE | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Concentration : 0.055 μg/μL | Storage Buffer : In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0 (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)