Name :
Recombinant Human Fibroblast Growth Factor Receptor 1(IIIb)
Specification :
| Cat. No. : FGFR1-485H | Description : Fibroblast growth factor receptor-1 alpha (FGFR1-alpha) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-alpha is expressed in prostate luminal epithelial cells. FGFR1alpha signals are posteriorizing factors that control node regression and posterior embryonic development. FGFR1-alpha is a splice variant of FGFR1 containing the first immunoglobulin-like domain, whereas FGFR1-beta lacks this domain. The presence or absence of this N-terminal domain influences the affinity of the receptor towards aFGF and heparin. | Source : Mammalian cells | Molecular Weight : The predicted molecular weight of Recombinant Human FGF R1α (IIIb) is Mr 66 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110-120 kDa. | State Of Matter : Lyophilized. | Purity : > 95% by SDS Page and analyzed by silver stain. | Endotoxin : | Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Information :
| Gene Name : FGFR1 fibroblast growth factor receptor 1 [ Homo sapiens ] | Synonyms : FGFR1; fibroblast growth factor receptor 1; CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR; N-SAM; FLJ99988; OTTHUMP00000190881; soluble FGFR1 variant 1; FMS-like tyrosine kinase 2; ydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1 | Gene ID : 2260 | mRNA Refseq : NM_015850 | Protein Refseq : NP_056934 | UniProt ID : P11362 | Chromosome Location : 8p12 | MIM : 607401 | Pathway : Adherens junction; MAPK signaling pathway; elanoma; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Axon guidance; Signaling by FGFR | Function : ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; transferase activity
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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