Name :
Recombinant Human Fibroblast Growth Factor Receptor 2
Specification :
| Cat. No. : FGFR2-5002H | Description : Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorigenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4 are known. | Source : Human | Host : Insect cells | Form : Supplied as a lyophilized powder with no preservative. Reconstitute in sterile water to a concentration > 0.05mg/ml. | Purity : >90% pure by SDS PAGE | Molecular Mass : 170 kDa (dimer, glycosylated) | Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions | Endotoxin Levels : | Storage : Store at -70 deg C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 deg C. Avoid repeated freeze/thaw cycles.
Gene Information :
| Gene Name : FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ] | Official Symbol : FGFR2 | Synonyms : FGFR2; fibroblast growth factor receptor 2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FLJ98662; KSAR; FGFR-2; KSAM; OTTHUMP00000020621; OTTHUMP00000020629; BEK fibroblast growth factor receptor; CD332 antigen; FGF receptor; Jackson-Weiss syndrome; Keratinocyte growth factor receptor 2; bacteria-expressed kinase; craniofacial dysostosis 1; fibroblast growth factor receptor 2; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; protein tyrosine kinase, receptor like 14; soluble FGFR4 variant 4 | Gene ID : 2263 | mRNA Refseq : NM_000141 | Protein Refseq : NP_000132 | MIM : 176943 | UniProt ID : P21802 | Chromosome Location : 10q26 | Pathway : Endocytosis; MAPK signaling pathway; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR | Function : ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; receptor activity; transferase activity
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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