Name :
Recombinant Human Fibroblast Growth Factor Receptor 3
Specification :
| Cat. No. : FGFR3-5003H | Description : Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorigenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4 are known. | Source : Human | Host : Insect cells | Form : Supplied as a lyophilized powder with no preservative. Reconstitute in sterile water to a concentration > 0.05mg/ml. | Purity : >90% pure by SDS PAGE | Molecular Mass : 170 kDa | Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions | Endotoxin Levels : | Storage : Store at -70 deg C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 deg C. Avoid repeated freeze/thaw cycles.
Gene Information :
| Gene Name : FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] | Official Symbol : FGFR3 | Synonyms : FGFR3; fibroblast growth factor receptor 3; ACH; CEK2; JTK4; CD333; HSFGFR3EX; OTTHUMP00000149958; OTTHUMP00000149959; tyrosine kinase JTK4; hydroxyaryl-protein kinase; achondroplasia, thanatophoric dwarfism; EC 2.7.10.1; FGFR-3; CD333 antigen | Gene ID : 2261 | mRNA Refseq : NM_000142 | Protein Refseq : NP_000133 | MIM : 134934 | UniProt ID : P22607 | Chromosome Location : 4p16.3 | Pathway : Bladder cancer; Endocytosis; MAPK signaling pathway; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR | Function : ATP binding; fibroblast growth factor receptor activity; identical protein binding; nucleotide binding; receptor activity; transferase activity
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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