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Name :
Recombinant Human FLT3, GST-His

Specification :
| Cat. No. : FLT3-688H | Description : Flt-3 belongs to the class III receptor tyrosine kinase family that is closely related to c-Kit and c-Fms. It is expressed in primitive hematopoietic cells and its ligand exerts proliferative effects on these cells in vitro in cooperation with other cytokines. Flt-3 is also expressed in the placenta, testis, spleen, thymus, bone marrow, brain and in cerebellar Purkinje cells. | Source : S. frugiperda. | Form : Liquid. In 100 mM NaCl, 50 mM Tris-HCl, 15 mM reduced glutathione, 5 mM DTT, 20% glycerol, pH 8.0. Please refer to vial label for lot-specific concentration. | Unit Definition : One unit is defined as the amount of enzyme required to transfer 1 nmol phosphate to Poly(Glu,Tyr)4:1 per min at 30°C, using variable concentrations of ATP (0.1-12.6 µM). | Specific Activity : ≥28 U/mg protein. | Toxicity : Standard Handling (MSDS available upon request). | Storage : ≤ -70°C. Avoid freeze/thaw Following initial thaw, aliquot and freeze (-70°C).

Gene Information :
| Gene Name : FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ] | Synonyms : FLT3; fms-related tyrosine kinase 3; FLK2; STK1; CD135; CD135 antigen; fetal liver kinase 2; FL cytokine receptor; tal liver kinase 2; stem cell tyrosine kinase 1; FLT3 receptor tyrosine kinase; tyrosine-protein kinase receptor FLT3; growth factor receptor tyrosine kinase type III; C 2.7.10.1; OTTHUMP00000042340; fetal liver kinase 2 | Gene ID : 2322 | mRNA Refseq : NM_004119 | Protein Refseq : NP_004110 | MIM : 136351 | UniProt ID : P36888 | Chromosome Location : 13q12 | Pathway : ute myeloid leukemia; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Pathways in cancer | Function : ATP binding; nucleotide binding; osphoinositide 3-kinase binding; protein binding; receptor activity; transferase activity; vascular endothelial growth factor receptor activity

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Author: Cholesterol Absorption Inhibitors