Recombinant Human Fms-Related Tyrosine Kinase 3, GST-tagged

Specification :
| Cat. No. : FLT3-1016H | Description : FLT3 is a receptor tyrosine kinase that has been shown to play a role in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors. FLT3 consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. FLT3 is the most frequently mutated gene in cases of acute myelogenous leukemia (AML). | Applications : Kinase Assay; Western Blot | Molecular Weight : 73 kDa | Expression System : Sf9 insect cells using baculovirus | Species : Human | Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol. | Specific Activity : 70 nmol/min/mg | Purity : >75% | Concentration : 0.1 ug/ul | Sequences : 571-993 | Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Pathways : Cytokine-cytokine receptor interaction; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Pathways in cancer