Recombinant Human FZD4 Protein

Specification :
| Description : This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq | Source : Wheat Germ | Species : Human | Form : Liquid | Molecular Mass : 59.9 kDa | AA Sequence : MAWRGAGPSVPGAPGGVGLSLGLLL QLLLLLGPARGFGDEEERRCDPIRI SMCQNLGYNVTKMPNLVGHELQTDA ELQLTTFTPLIQYGCSSQLQFFLCS VYVPMCTEKINIPIGPCGGMCLSVK RRCEPVLKEFGFAWPESLNCSKFPP QNDHNHMCMEGPGDEEVPLPHKTPI QPGEECHSVGTNSDQYIWVKRSLNC VLKCGYDAGLYSRSAKEFTDIWMAV WASLCFISTAFTVLTFLIDSSRFSY PERPIIFLSMCYNIYSIAYIVRLTV GRERISCDFEEAAEPVLIQEGLKNT GCAIIFLLMYFFGMASSIWWVILTL TWFLAAGLKWGHEAIEMHSSYFHIA AWAIPAVKTIVILIMRLVDADELTG LCYVGNQNLDALTGFVVAPLFTYLV IGTLFIAAGLVALFKIRSNLQKDGT KTDKLERLMVKIGVFSVLYTVPATC VIACYFYEISNWALFRYSADDSNMA VEMLKIFMSLLVGITSGMWIWSAKT LHTWQKCSNRLVNSGKVKREKRGNG WVKPGKGSETVV | Applications : Antibody ProductionFunctional StudyCompound Screening | Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis. | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.