Recombinant Human GAK Protein, Myc/DDK-tagged

Specification :
| Description : In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the ‘cyclin box.’ In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. | Source : HEK293T | Species : Human | Tag : Myc/DDK | Molecular Mass : 143 kDa | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 μg/mL as determined by microplate BCA method | Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol