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Name :
Recombinant Human GLI1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 117.9 kDa | AA Sequence : MFNSMTPPPISSYGEPCCLRPLPSQ GAPSVGTEGLSGPPFCHQANLMSGP HSYGPARETNSCTEGPLFSSPRSAV KLTKKRALSISPLSDASLDLQTVIR TSPSSLVAFINSRCTSPGGSYGHLS IGTMSPSLGFPAQMNHQKGPSPSFG VQPCGPHDSARGGMIPHPQSRGPFP TCQLKSELDMLVGKCREEPLEGDMS SPNSTGIQDPLLGMLDGREDLEREE KREPESVYETDCRWDGCSQEFDSQE QLVHHINSEHIHGERKEFVCHWGGC SRELRPFKAQYMLVVHMRRHTGEKP HKCTFEGCRKSYSRLENLKTHLRSH TGEKPYMCEHEGCSKAFSNASDRAK HQNRTHSNEKPYVCKLPGCTKRYTD PSSLRKHVKTVHGPDAHVTKRHRGD GPLPRAPSISTVEPKREREGGPIRE ESRLTVPEGAMKPQPSPGAQSSCSS DHSPAGSAANTDSGVEMTGNAGGST EDLSSLDEGPCIAGTGLSTLRRLEN LRLDQLHQLRPIGTRGLKLPSLSHT GTTVSRRVGPPVSLERRSSSSSSIS SAYTVSRRSSLASPFPPGSPPENGA SSLPGLMPAQHYLLRARYASARGGG TSPTAASSLDRIGGLPMPPWRSRAE YPGYNPNAGVTRRASDPAQAADRPA PARVQRFKSLGCVHTPPTVAGGGQN FDPYLPTSVYSPQPPSITENAAMDA RGLQEEPEVGTSMVGSGLNPYMDFP PTDTLGYGGPEGAAAEPYGARGPGS LPLGPGPPTNYGPNPCPQQASYPDP TQETWGEFPSHSGLYPGPKALGGTY SQCPRLEHYGQVQVKPEQGCPVGSD STGLAPCLNAHPSEGPPHPQPLFSH YPQPSPPQYLQSGPYTQPPPDYLPS EPRPCLDFDSPTHSTGQLKAQLVCN YVQSQQELLWEGGGREDAPAQEPSY QSPKFLGGSQVSPSRAKAPVNTYGP GFGPNLPNHKSGSYPTPSPCHENFV VGANRASHRAAAPPRLLPPLPTCYG PLKVGGTNPSCGHPEVGRLGGGPAL YPPPEGQVCNPLDSLDLDNTQLDFV AILDEPQGLSPPPSHDQRGSSGHTP PPSGPPNMAVGNMSVLLRSLPGETE FLNSSATRTRPLEQKLISEEDLAAN DILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : GLI1 GLI family zinc finger 1 [ Homo sapiens (human) ] | Official Symbol : GLI1 | Synonyms : GLI1; GLI family zinc finger 1; GLI, glioma associated oncogene family zinc finger 1, glioma associated oncogene homolog 1 (zinc finger protein); zinc finger protein GLI1; oncogene GLI; glioma-associated oncogene 1; glioma-associated oncogene homolog 1 (zinc finger protein); GLI; | Gene ID : 2735 | mRNA Refseq : NM_005269 | Protein Refseq : NP_005260 | MIM : 165220 | UniProt ID : P08151

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors