Name :
Recombinant Human GP9, His-tagged
Specification :
| product overview : Recombinant human GP9 protein, fused to His-tag at N-terminus, was expressed in E.coli. | description : GP9 is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. | source : E. coli | species : Human | tag : His | form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol | molecular mass : 16.8 kDa (154aa) | protein length : 17-147aa | aa sequence : MGSSHHHHHH SSGLVPRGSH MGSTKDCPSP CTCRALETMG LWVDCRGHGL TALPALPART RHLLLANNSL QSVPPGAFDH LPQLQTLDVT QNPWHCDCSL TYLRLWLEDR TPEALLQVRC ASPSLAAHGP LGRLTGYQLG SCGWQLQASW VRPG | purity : >90% by SDS – PAGE | applications : SDS-PAGE | storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. | concentration : 1 mg/ml
Gene Information :
| gene name : GP9 glycoprotein IX (platelet) [ Homo sapiens ] | official symbol : GP9 | synonyms : GP9; glycoprotein IX (platelet); platelet glycoprotein IX; CD42a; GPIX; GP-IX; glycoprotein 9; | Gene ID : 2815 | mrna refseq : NM_000174 | protein refseq : NP_000165 | mim : 173515 | uniprot id : P14770 | chromosome location : 3q21.3 | pathway : ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; GP1b-IX-V activation signalling, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Hemostasis, organism-specific biosystem;
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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