Recombinant Human GRK2 Protein (2-221 aa), His-tagged

Specification :
| Description : Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. | Source : E. coli | Species : Human | Tag : His | Form : Tris-based buffer,50% glycerol | Molecular Mass : 29.6 kDa | Protein length : 2-221 aa | AA Sequence : ADLEAVLADVSYLMAMEKSKATPAA RASKKILLPEPSIRSVMQKYLEDRG EVTFEKIFSQKLGYLLFRDFCLNHL EEARPLVEFYEEIKKYEKLETEEER VARSREIFDSYIMKELLACSHPFSK SATEHVQGHLGKKQVPPDLFQPYIE EICQNLRGDVFQKFIESDKFTRFCQ WKNVELNIHLTMNDFSVHRIIGRGG FGEVYGCRKADTGKMYAMKC | Purity : > 90% as determined by SDS-PAGE. | Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. | Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. | Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.