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Name :
Recombinant Human GRK4 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 66.6 kDa | AA Sequence : MELENIVANSLLLKARQGGYGKKSG RSKKWKEILTLPPVSQCSELRHSIE KDYSSLCDKQPIGRRLFRQFCDTKP TLKRHIEFLDAVAEYEVADDEDRSD CGLSILDRFFNDKLAAPLPEIPPDV VTECRLGLKEENPSKKAFEECTRVA HNYLRGEPFEEYQESSYFSQFLQWK WLERQPVTKNTFRHYRVLGKGGFGE VCACQVRATGKMYACKKLQKKRIKK RKGEAMALNEKRILEKVQSRFVVSL AYAYETKDALCLVLTIMNGGDLKFH IYNLGNPGFDEQRAVFYAAELCCGL EDLQRERIVYRDLKPENILLDDRGH IRISDLGLATEIPEGQRVRGRVGTV GYMAPEVVNNEKYTFSPDWWGLGCL IYEMIQGHSPFKKYKEKVKWEEVDQ RIKNDTEEYSEKFSEDAKSICRMLL TKNPSKRLGCRGEGAAGVKQHPVFK DINFRRLEANMLEPPFCPDPHAVYC KDVLDIEQFSAVKGIYLDTADEDFY ARFATGCVSIPWQNEMIESGCFKDI NKSESEEALPLDLDKNIHTPVSRPN RGFFYRLFRRGGCLTMVPSEKEVEP KQCTRTRPLEQKLISEEDLAANDIL DYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : GRK4 G protein-coupled receptor kinase 4 [ Homo sapiens (human) ] | Official Symbol : GRK4 | Synonyms : GRK4; G protein-coupled receptor kinase 4; G protein coupled receptor kinase 2 like (Drosophila), GPRK2L; GPRK4; ITI1; IT11; GRK4a; GPRK2L; | Gene ID : 2868 | mRNA Refseq : NM_182982 | Protein Refseq : NP_892027 | MIM : 137026 | UniProt ID : P32298

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors