Recombinant Human HAVCR2 Protein (ECD), His-tagged(C-ter)

Specification :
| Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] | Source : HEK293 | Species : Human | Tag : His(C-ter) | Form : Powder | Protein Length : Ser22-Arg200 | Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. | Purity : > 97% (by SDS-PAGE) | Applications : Binding, SDS-PAGE | Notes : For laboratory research only, not for drug, diagnostic or other use. | Storage : Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. | Storage Buffer : PBS (pH 7.4) | Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.