Recombinant Human HAVCR2 Protein, Fc-tagged

Specification :
| Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. | Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized | Molecular Mass : 42 kDa | Protein Length : 301 | AA Sequence : MFSHLPFDCVLLLLLLLLTRSSEVE YRAEVGQNAYLPCFYTPAAPGNLVP VCWGKGACPVFECGNVVLRTDERDV NYWTSRYWLNGDFRKGDVSLTIENV TLADSGIYCCRIQIPGIMNDEKFNL KLVIKPAKVTPAPTRQRDFTAAFPR MLTTRGHGPAETQTLGSLPDINLTQ ISTLANELRDSRLANDLRDSGATIR IGIYIGAGICAGLALALIFGALIFK WYSHSKEKIQNLSLISLANLPPSGL ANAVAEGIRSEENIYTIEENVYEVE EPNEYYCYVSSRQQPSQPLGCRFAM P | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.