Name :
Recombinant Human HAVCR2 Protein, hIgG-His-Tagged
Specification :
| Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. | Source : Baculovirus | Species : Human | Tag : hIgG-His | Form : Liquid | Molecular Mass : 47.3 kDa | Protein Length : 423aa | Endotoxin : | Purity : > 85% by SDS-PAGE | Applications : SDS-PAGE | Notes : Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use. | Storage : Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. | Concentration : 0.5mg/ml (determined by absorbance at 280nm) | Storage Buffer : Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerolPurity> 85% by SDS-PAGE
Gene Information :
| Gene Name : HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens (human) ] | Official Symbol : HAVCR2 | Synonyms : Hepatitis A virus cellular receptor 2, HAVCR2, HAVcr-2, KIM-3, Tim-3, TIM3, TIMD-3, TIMD3, FLJ14428, HAVcr-2, Havcr2, HAVR2_HUMAN, Hepatitis A virus cellular receptor 2, Kidney injury molecule 3, KIM 3, KIM3, T cell immunoglobulin and mucin domain containing 3, T cell immunoglobulin mucin 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, Tim 3, TIM-3, TIM3, TIMD-3, TIMD3 | Gene ID : 84868 | mRNA Refseq : NM_032782.5 | Protein Refseq : NP_116171.3 | MIM : 606652 | UniProt ID : Q8TDQ0
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