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Name :
Recombinant Human HES1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 29.4 kDa | AA Sequence : MPADIMEKNSSSPVAATPASVNTTP DKPKTASEHRKSSKPIMEKRRRARI NESLSQLKTLILDALKKDSSRHSKL EKADILEMTVKHLRNLQRAQMTAAL STDPSVLGKYRAGFSECMNEVTRFL STCEGVNTEVRTRLLGHLANCMTQI NAMTYPGQPHPALQAPPPPPPGPGG PQHAPFAPPPPLVPIPGGAAPPPGG APCKLGSQAGEAAKVFGGFQVVPAP DGQFAFLIPNGAFAHSGPVIPVYTS NSGTSVGPNAVSPSSGPSLTADSMW RPWRNTRTRPLEQKLISEEDLAAND ILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : HES1 hes family bHLH transcription factor 1 [ Homo sapiens (human) ] | Official Symbol : HES1 | Synonyms : HES1; hairy and enhancer of split 1, (Drosophila); hairy homolog (Drosophila), HRY; transcription factor HES-1; bHLHb39; FLJ20408; HES 1; Hes1; hairy homolog; hairy-like protein; class B basic helix-loop-helix protein 39; HHL; HRY; HES-1; | Gene ID : 3280 | mRNA Refseq : NM_005524 | Protein Refseq : NP_005515 | MIM : 139605 | UniProt ID : Q14469

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors