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Name :
Recombinant Human ICAM3, His-tagged

Specification :
| Description : The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. | Source : E.coli | Species : Human | Tag : His | Protein length : 200-547a.a. | Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. | Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information :
| Gene Name : ICAM3 intercellular adhesion molecule 3 [ Homo sapiens ] | Official Symbol : ICAM3 | Synonyms : ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM R; ICAM-3; intercellular adhesion molecule-3; ICAM-R; | Gene ID : 3385 | mRNA Refseq : NM_002162 | Protein Refseq : NP_002153 | MIM : 146631 | UniProt ID : P32942 | Chromosome Location : 19p13.3-p13.2 | Pathway : Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; | Function : integrin binding; protein binding; receptor binding;

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Author: Cholesterol Absorption Inhibitors